Analysis of White Matter Damage in Patients with Multiple Sclerosis via a Novel In Vivo MR Method for Measuring Myelin, Axons, and G-Ratio.
Akifumi HagiwaraMasaaki HoriKazumasa YokoyamaM NakazawaUeda RyoM HoritaChristina AndicaSusumu MoriShigeki AokiPublished in: AJNR. American journal of neuroradiology (2017)
In this in vivo MR imaging study, the myelin of WM was more damaged than axons in plaques and periplaque WM of patients with MS. Myelin and axon volume fractions and g-ratio may potentially be useful for evaluating WM damage in patients with MS.