HLA binding-groove motifs are associated with myocarditis induction after Pfizer-BioNTech BNT162b2 vaccination.

Aviran AharonGil BenedekBarhoum BarhoumElchanan ParnasaNur MagadleOfer PerzonDror Mevorach

Published in: European journal of clinical investigation (2023)

Our findings suggest that immunogenetic fingerprints in HLA peptide-binding grooves may affect the presentation of peptides derived from the Pfizer-BioNTech BNT162b2 vaccination to T cells and induce an inflammatory process that results in myocarditis.

Keyphrases

dna binding
binding protein
oxidative stress