Comparative analysis of uninduced and neuronally-induced human dental pulp stromal cells in a 6-OHDA model of Parkinson's disease.

Evellyn M AzevedoLetícia FracaroAgner H D HochuliJéssica IlkiwEllen L BailMateus de O LisboaLais S RodriguesFabiane BarchikiAlejandro CorreaLuiz G A CapriglionePaulo R S BrofmanMarcelo M S Lima

Published in: Cytotherapy (2024)

Our results suggested that uninduced DPSCs and neuronally-induced DPSCs exhibit potential in reducing dopaminergic neuron loss and improving locomotor behavior, but their underlying mechanisms differ.

Keyphrases

high glucose
endothelial cells
diabetic rats
spinal cord injury
drug induced
induced pluripotent stem cells