Kratom use disorder and unfolded protein response: Evaluating their relationship in a case control study.

Bin YangMei Lan TanRuiling ZhangDarshan SinghMohammad Farris Iman Leong Bin Abdullah

Published in: PloS one (2023)

Regular kratom use may induce protracted ER stress, leading to the decompensation of the unfolded protein response to maintain ER homeostasis. This effect may be linked to kratom use disorder occurrence.

Keyphrases

endoplasmic reticulum
endoplasmic reticulum stress
protein protein
risk assessment
amino acid
estrogen receptor