NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.

Wei GuoYunhe ZhaoHouxuan LiLang Lei

Published in: Journal of periodontal research (2021)

NCOA4-ferritinophagy participated in the progress of periodontitis progression. P. gingvalis-triggered ferritinophagy aggravated production of ROS and inflammatory responses in PDLFS. These findings suggest iron homeostasis plays an important role in the pathogenesis of periodontitis.

Keyphrases

cell death
dna damage
oxidative stress