Efficacy and safety of lamotrigine in pediatric mood disorders: A systematic review.

Rakesh KumarJuan GarzonDeniz YurukLeslie C HassettMaria SalibaCan OzgerCinar OztosunKelly AhernArjun P AthreyaBalwinder Singh Paul E Croarkin Jennifer L Vande Voort

Published in: Acta psychiatrica Scandinavica (2022)

Most studies suggested that LAM was safe and effective in pediatric patients with mood disorders. However, the data regarding the therapeutic range for LAM are lacking. Based on the data, there is inconsistent evidence to make conclusive recommendations on therapeutic LAM dosage for mood improvement in the pediatric population. Further studies including larger sample sizes are required to address this relevant clinical question.

Keyphrases

bipolar disorder
sleep quality
electronic health record
big data
case control
data analysis
depressive symptoms
physical activity
machine learning
artificial intelligence
young adults