Higher fasting plasma FGF21 concentration is associated with lower ad libitum soda consumption in humans.

Alessio BasoloTim HollsteinMujtaba H ShahMary WalterJonathan KrakoffSusanne B VotrubaPaolo Piaggi

Published in: The American journal of clinical nutrition (2021)

Higher plasma fasting FGF21 concentration is associated with lower ad libitum soda intake. Although this inverse correlation does not imply causation, the present results support the putative role of FGF21 in the reward pathways regulating sugar consumption in humans. This trial was registered at www.clinicaltrials.gov as NCT00342732.

Keyphrases

blood glucose
insulin resistance
clinical trial
phase ii
adipose tissue
blood pressure
skeletal muscle
prefrontal cortex