Radiosurgery or hypofractionated stereotactic radiotherapy for brain metastases from radioresistant primaries (melanoma and renal cancer).

Paul LesueurJustine LequesneVictor BarrauxWilliam KaoJulien GeffrelotJean-Michel GrellardJean-Louis HabrandEvelyne EmeryBrigitte MarieJuliette ThariatDinu Stefan

Published in: Radiation oncology (London, England) (2018)

Fractionation does not decrease LPFS. Even for small radioresistant brain metastases (< 3 cm), HFSRT, with 3 or 6 fractions, leads to an excellent local control rate of 72% at 1 year with a rate of 7.1% of radionecrosis. HFSRT is a safe and efficient alternative treatment to SRS.

Keyphrases

brain metastases
small cell lung cancer
early stage
radiation therapy
squamous cell
locally advanced
squamous cell carcinoma
replacement therapy
basal cell carcinoma