SARS-CoV-2 RNA in plasma samples of COVID-19 affected individuals: a cross-sectional proof-of-concept study.

Luna ColagrossiMaria AntonelloSilvia RenicaMarco MerliElisa MatarazzoGiovanna TraviMarta VecchiJacopo ColomboAntonio MuscatelloGiacomo GrasselliSilvia Nerini MolteniVittorio ScaravilliEmanuele CattaneoDiana FantiChiara VismaraAlessandra BanderaAndrea GoriMassimo PuotiValeria CentoClaudia AlteriCarlo Federico Perno

Published in: BMC infectious diseases (2021)

Even if based on a small sample population, this proof-of-concept study poses the basis for an early identification of patients at higher risk of SARS-CoV-2 viremia, and therefore likely to develop severe COVID-19, and supports the need of a quantitative viral load determination in blood and respiratory samples of haematologic patients with COVID-19 in order to predict prognosis and consequently to help their further management.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
high resolution
solid phase extraction
molecularly imprinted
drug induced