Serum neurofilament light chain at time of diagnosis is an independent prognostic factor of survival in amyotrophic lateral sclerosis.
E ThouvenotC DematteiS LehmannA Maceski-MaleskaC HirtzR Juntas-MoralesN PageotF EsselinS AlphandéryT VincentWilliam CamuPublished in: European journal of neurology (2019)
Higher sNfL concentration is a strong and independent prognostic factor of death in ALS as early as the time of diagnosis.