The risk of malignancy of atypical urothelial cells of undetermined significance in patients treated with chemohyperthermia or electromotive drug administration.

Francesco Pierconti Esther Diana RossiPatrizia StracciaGuido FaddaLuigi Maria LaroccaPier Francesco BassiEmilio SaccoGiovanni Schinzari

Published in: Cancer cytopathology (2018)

In the urine samples from patients treated with EMDA/MMC or C-HT/MMC, a diagnosis of SHGUC could be made even on degenerated urothelial cells when considering cellular degeneration as a "physiological" consequence of the treatment that involves either normal or neoplastic cells. Cancer Cytopathol 2018;126:200-6. © 2018 American Cancer Society.

Keyphrases

induced apoptosis
cell cycle arrest
papillary thyroid
high grade
oxidative stress
signaling pathway
drug administration