Intracranial Carotid Arteriosclerosis Mediates the Association Between Blood Pressure and Cerebral Small Vessel Disease.
Jesús D MelgarejoMeike W VernooijMohammad Arfan IkramZhen-Yu ZhangDaniel BosPublished in: Hypertension (Dallas, Tex. : 1979) (2022)
Intracranial arteriosclerosis mediates the association between BP and CSVD. Internal elastic lamina calcification, considered a proxy of arterial stiffness, is the leading mechanism explaining the link between BP and CSVD.