A common regulatory haplotype doubles lactoferrin concentration in milk.
Thomas John LopdellAlexander J TrevartonJanelle MoodyClaire Prowse-WilkinsSarah KnowlesKathryn TipladyAmanda J ChamberlainMichael E GoddardRichard J SpelmanKlaus LehnertRussell G SnellStephen R DavisMathew D LittlejohnPublished in: Genetics, selection, evolution : GSE (2024)
Here, we report a regulatory haplotype of 115 variants with conspicuously large impacts on milk lactoferrin concentration. These findings could enable the selection of animals for high-producing specialist herds.