Oxidized SOD1 accelerates cellular senescence in neural stem cells.

Teng GuanYing GuoTing ZhouQiang YuJingyi SunBaoliang SunGuohui ZhangJiming Kong

Published in: Stem cell research & therapy (2024)

Oxidized hSOD1 is a causal factor in the cellular senescence of NSCs. The removal of oxidized hSOD1 is a strategy to rejuvenate NSCs and to improve the quality of EVs derived from senescent cells.

Keyphrases

low density lipoprotein
neural stem cells
dna damage
induced apoptosis
endothelial cells
stress induced
cell proliferation