Trajectories of cognitive processing speed and physical disability over 11 years following initiation of a first multiple sclerosis disease-modulating therapy.
Elisa LonginettiSimon EnglundJoachim BurmanKatharina FinkAnna Fogdell-HahnMartin GunnarssonJan A HillertAnnette Magdalene Langer-GouldJan N LyckePetra NilssonJonatan SalzerAnders SvenningssonJohan MellergårdTomas OlssonFredrik PiehlThomas FrisellPublished in: Journal of neurology, neurosurgery, and psychiatry (2023)
In this cohort of actively treated RRMS, patients' processing speed remained stable over the years following DMT start, whereas patients with moderate physical disability deteriorated in physical function. Nevertheless, there was a strong link between processing speed and disability after DMT start.