Phenotypic Impact of Rare Potentially Damaging Copy Number Variation in Obsessive-Compulsive Disorder and Chronic Tic Disorders.

Behrang MahjaniRebecca BirnbaumAriela Buxbaum GriceCarolina CappiSeulgi JungMarina Natividad AvilaAbraham ReichenbergSven SandinChristina M HultmanJoseph D BuxbaumDorothy E Grice

Published in: Genes (2022)

pdCNV represents part of the risk architecture for OCD and CTD. If replicated, our findings suggest pdCNV impact some OCD symptoms. Genes within the 16p13.11 region are potential OCD risk genes.

Keyphrases

obsessive compulsive disorder
copy number
genome wide
deep brain stimulation
mitochondrial dna
dna methylation
gene expression
depressive symptoms
climate change
drug induced
human health