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Cleaning protocols in forensic genetic laboratories.

Marie-Louise KampmannJacob Tfelt HansenClaus Børsting
Published in: International journal of legal medicine (2024)
It is pivotal to avoid cross-sample contamination in forensic genetic laboratories and optimal cleaning protocols for the removal of DNA are essential. A survey was performed, and ten forensic genetic laboratories shared their cleaning protocols in pre-PCR and post-PCR laboratories. The cleaning frequencies on different surface areas were somewhat similar, whereas none of the laboratories used the same cleaning reagents. Therefore, the efficiencies of the cleaning protocol utilised were tested and compared. The results showed that freshly made household bleach and Virkon® removed all amplifiable DNA from the surfaces, whereas DNA AWAY™ and the disinfection reagents ethanol, isopropanol, and ChemGene HLD 4 L did not.
Keyphrases
  • circulating tumor
  • cell free
  • single molecule
  • genome wide
  • drinking water
  • copy number
  • risk assessment
  • escherichia coli
  • nucleic acid
  • dna methylation
  • heavy metals
  • human health
  • biofilm formation