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Repair of Limb Ischemia Is Dependent on Hematopoietic Stem Cell Specific-SHP-1 Regulation of TGF-β1.

Chen WangRavi NistalaMin CaoDe-Pei LiYi PanMojgan GolzyYuqi CuiZhenguo LiuXunlei Kang
Published in: Arteriosclerosis, thrombosis, and vascular biology (2022)
HSPC-SHP-1-mediated regulation of TGF-β1 in both bone marrow and peripheral blood is required for a normal response to ischemic stress.
Keyphrases
  • hematopoietic stem cell
  • peripheral blood
  • bone marrow
  • transforming growth factor
  • mesenchymal stem cells
  • epithelial mesenchymal transition
  • ischemia reperfusion injury
  • stress induced
  • brain injury