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Angiotensin-1-converting enzyme inhibition, antioxidant activity, and modulation of cerebral Na+/K+ ATPase by free phenolics of African locust bean (Parkia biglobosa).

Kayode KomolafeAfolabi C AkinmoladunTitilope R KomolafeMary T OlaleyeAline A BoligonAkintunde A AkindahunsiJoao B T Rocha
Published in: Health science reports (2017)
The effects of P biglobosa on ACE and cerebral ATPase are related to its constituent phenolics. ACE inhibition could be an important mechanism underlying the documented hypotensive effect of the plant.
Keyphrases
  • angiotensin converting enzyme
  • angiotensin ii
  • subarachnoid hemorrhage
  • endoplasmic reticulum
  • drug induced