Absence of MyD88 from Skeletal Muscle Protects Female Mice from Inactivity-Induced Adiposity and Insulin Resistance.

Ziad S MahmassaniPaul T ReidyAlec I McKenzieJonathan J PetrocelliO'Connor MatthewsNaomi M de HartPatrick J FerraraRyan M O'ConnellKatsuhiko FunaiMicah J Drummond

Published in: Obesity (Silver Spring, Md.) (2020)

Whole-body miR146a-/- exacerbated inactivity-induced fat gain and muscle insulin resistance, whereas MusMyD88-/- prevented insulin resistance in female mice.

Keyphrases

insulin resistance
skeletal muscle
high fat diet induced
adipose tissue
high fat diet
metabolic syndrome
high glucose
polycystic ovary syndrome
diabetic rats
type diabetes
cell proliferation
long non coding rna
drug induced
toll like receptor
oxidative stress
weight loss
physical activity
wild type
endothelial cells