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Mitofusin-2 Regulates Platelet Mitochondria and Function.

Shancy JacobYasuhiro KosakaSeema BhatlekarFrederik DenormeHaley BenzonAlexandra MoodyVictoria MoodyEmilia A TugolukovaGrayson HullNina KishimotoBhanu K ManneLi GuoRhonda A SouvenirBrayden J SeligerAlicia S EustesKelly HoergerNeal D TolleyAmir Nima FatahianSihem BoudinaDavid Chistopher ChristianiYong-Yue WeiCan JuRobert A CampbellMatthew T RondinaE Dale AbelPaul F BrayAndrew S WeyrichJesse W Rowley
Published in: Circulation research (2023)
Mfn2 preserves mitochondrial phenotypes in megakaryocytes and platelets and influences platelet life span, function, and outcomes of stroke and lung injury.
Keyphrases
  • atrial fibrillation
  • cell death
  • type diabetes
  • reactive oxygen species
  • skeletal muscle
  • brain injury
  • weight loss