A comprehensive profiling of renin-angiotensin system in mouse and human plasma by a rapid quantitative analysis of 14 angiotensin peptides using ultrahigh-performance liquid chromatography with tandem mass spectrometry.
Yamin LiuLinnan LiZhengtao WangLi YangPublished in: Rapid communications in mass spectrometry : RCM (2023)
The method is currently reported to allow the largest number of Ang peptide species to be detected at one time. In addition, the proposed method offers a fast and reliable approach for comprehensive analysis of Ang metabolism in biological samples, facilitating research on the physiological and pathological states of cardiovascular, kidney and respiratory diseases.
Keyphrases
- tandem mass spectrometry
- liquid chromatography
- ultra high performance liquid chromatography
- angiotensin ii
- high performance liquid chromatography
- mass spectrometry
- high resolution mass spectrometry
- simultaneous determination
- gas chromatography
- solid phase extraction
- high resolution
- angiotensin converting enzyme
- loop mediated isothermal amplification
- sensitive detection
- quantum dots