Transcriptome-Wide Regulation of Key Developmental Pathways in the Mouse Neural Tube by Prenatal Alcohol Exposure.

Karen E BoschenTravis S PtacekJeremy M SimonScott E Parnell

Published in: Alcoholism, clinical and experimental research (2020)

These data give a comprehensive view of the changing landscape of the embryonic transcriptome networks in regions of the neural tube that give rise to brain structures impacted by a neurulation-stage alcohol exposure. Identification of gene networks dysregulated by alcohol will help elucidate the pathogenic mechanisms of alcohol's actions.

Keyphrases

alcohol consumption
single cell
genome wide
rna seq
gene expression
pregnant women
high resolution
multiple sclerosis
electronic health record
copy number
white matter
mass spectrometry
artificial intelligence
big data