Life-threatening toxicities upon Pembrolizumab intake: could pharmacokinetics be the bad guy?

Mourad HamimedRaynier DevillierPierre-Jean WeillerClémence MarinJean-Marc SchianoNawel BelmecheriMarie-Christine Etienne-GrimaldiJoseph CiccoliniSamia Harbi

Published in: Cancer chemotherapy and pharmacology (2023)

This case report suggests that persistent overexposure in plasma could lead to life-threatening toxicities with Pembrolizumab.

Keyphrases

case report
advanced non small cell lung cancer
physical activity