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Peptide-Decorated Tunable-Fluorescence Graphene Quantum Dots.

Bedanga SapkotaAbdelkrim BenabbasHao-Yu Greg LinWentao LiangPaul M ChampionMeni Wanunu
Published in: ACS applied materials & interfaces (2017)
We report here the synthesis of graphene quantum dots with tunable size, surface chemistry, and fluorescence properties. In the size regime 15-35 nm, these quantum dots maintain strong visible light fluorescence (mean quantum yield of 0.64) and a high two-photon absorption (TPA) cross section (6500 Göppert-Mayer units). Furthermore, through noncovalent tailoring of the chemistry of these quantum dots, we obtain water-stable quantum dots. For example, quantum dots with lysine groups bind strongly to DNA in solution and inhibit polymerase-based DNA strand synthesis. Finally, by virtue of their mesoscopic size, the quantum dots exhibit good cell permeability into living epithelial cells, but they do not enter the cell nucleus.
Keyphrases
  • quantum dots
  • energy transfer
  • sensitive detection
  • single molecule
  • single cell
  • cell free
  • molecular dynamics
  • room temperature
  • living cells