Platelet Factor 4 Antibodies and Severe AKI.

Charlotte ThomasRafia AliIsabel ParkHelena Kim Samuel A P Short Sarah Kaunfer Lavanya Durai Osman A Yilmam Tushar ShenoyElisabeth M BattinelliHanny Al-SamkariDavid E Leaf

Published in: Kidney360 (2023)

Among hospitalized adults, the presence of PF4 antibodies is independently associated with a 56% higher odds of developing severe AKI. Additional studies are needed to investigate potential mechanisms that may underlie these findings, such as pathogenic effects of PF4 antibodies on the microvasculature of the kidneys.

Keyphrases

acute kidney injury
early onset
risk assessment
drug induced
human health
case control