The first embryonic landscape of G-quadruplexes related to myogenesis.

Lijin GuoWeiling HuangQi WenSiyu ZhangFarhad BordbarZhengzhong XiaoQinghua Nie

Published in: BMC biology (2024)

This comprehensive study unravels the first embryonic genomic G4s landscape, highlighting the regulatory role of NFATC2 G4 in orchestrating transcriptional activity through promoter DNA methylation during myogenesis.

Keyphrases

dna methylation
transcription factor
gene expression
single cell
genome wide
copy number
heat shock