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Anti-GD2 antibody for radiopharmaceutical imaging of osteosarcoma.

Yingli FuJing YuIoanna LiatsouYong DuAnders JosefssonJessie R NedrowHans RindtJeffrey N BryanDara L KraitchmanRobert F Hobbs
Published in: European journal of nuclear medicine and molecular imaging (2022)
This study demonstrates the feasibility of targeting GD2 on OS cells and spontaneous OS canine tumors using hu3F8-based radiopharmaceutical imaging. Its ability to deliver an imaging payload in a targeted manner supports the utility of hu3F8 for precision imaging of OS and potential future use in radiopharmaceutical therapy.
Keyphrases
  • high resolution
  • cancer therapy
  • induced apoptosis
  • stem cells
  • photodynamic therapy
  • fluorescence imaging
  • risk assessment
  • cell death
  • cell proliferation
  • cell cycle arrest
  • cell therapy