Characterization of Squamous Cell Lung Cancers from Appalachian Kentucky.
Jinpeng LiuThilakam MuraliTianxin YuChunming LiuTheru A SivakumaranHunter N B MoseleyIgor B ZhulinHeidi L WeissEric B DurbinSally R EllingsonJinze LiuBin HuangBrent J HallahanCraig M HorbinskiKurt HodgesDana L NapierThèrése BocklageJoseph MuellerNathan L VanderfordDavid W FardoChi WangSusanne M ArnoldPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2018)
Our study is the first report to characterize genomic alterations in lung SQCC from AppKY. These findings suggest population differences in the genetics of lung SQCC between AppKY and U.S. populations, highlighting the importance of the relevant population when developing personalized treatment approaches for this disease.