Methylated DNA Markers in Voided Urine for the Identification of Clinically Significant Prostate Cancer.

Paras ShahWilliam R TaylorBrianna J GysbersBenjamin R GochanourDouglas W MahoneySara S ThenMary E DevensPatrick H FooteKaren A Doering Kelli N BurgerBrandon NikolaiMichael W KaiserHatim T AllawiJohn C ChevilleJohn B KisielMatthew T Gettman

Published in: Life (Basel, Switzerland) (2024)

MDMs assayed in urine offer high sensitivity and specificity for detection of clinically significant prostate cancer. Prospective evaluation is necessary to estimate discrimination of patients as first-line screening and as an adjunct to prostate-specific antigen (PSA) testing.

Keyphrases

prostate cancer
radical prostatectomy
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
cell free
circulating tumor
loop mediated isothermal amplification
quantum dots
patient reported