Synthetic peptides designed to modulate adiponectin assembly improve obesity-related metabolic disorders.

Lutz Hampe Cheng XuPaul W R HarrisJie ChenMing LiuMartin MiddleditchMazdak RadjainiaYu Wang Alok K Mitra

Published in: British journal of pharmacology (2017)

Targeting ERp44-adiponectin interactions with short peptides represents an effective strategy to treat of obesity-related metabolic disorders, such as insulin resistance and Type 2 diabetes.

Keyphrases

insulin resistance
type diabetes
metabolic syndrome
high fat diet induced
adipose tissue
high fat diet
skeletal muscle
polycystic ovary syndrome
glycemic control
weight loss
weight gain
amino acid
cancer therapy
physical activity