Prevalence of Pathologic N2/N3 Disease in Postmenopausal Women with Clinical N0 ER+/HER2- Breast Cancer.
Maire J AmlickeJihye ParkChris B AgalaDana L CaseyEmily M RayStephanie M Downs-CannerPhilip M SpanheimerPublished in: Annals of surgical oncology (2022)
In postmenopausal women with cN0 ER+/HER2- breast cancer, the prevalence of pN2/N3 disease is low, indicating a potential opportunity to use the results of RxPONDER to extend criteria to omit SLNB. Prospective study is needed to determine safety, including risk of nodal recurrence, of omission of SLNB in carefully selected patients.
Keyphrases
- postmenopausal women
- bone mineral density
- end stage renal disease
- risk factors
- neoadjuvant chemotherapy
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- estrogen receptor
- lymph node
- breast cancer cells
- lymph node metastasis
- squamous cell carcinoma
- body composition
- radiation therapy
- patient reported
- young adults