Pan-Cancer Interrogation of MUTYH Variants Reveals Biallelic Inactivation and Defective Base Excision Repair Across a Spectrum of Solid Tumors.
Channing J PallerHanna TukachinskyAlexandra MaertensBrennan DeckerJulian R SampsonJeremy P CheadleEmmanuel S AntonarakisPublished in: JCO precision oncology (2024)
locus and defective BER. However, the effect is modest and requires confirmation in additional studies before being clinically actionable.