Didymin protects pancreatic beta cells by enhancing mitochondrial function in high-fat diet-induced impaired glucose tolerance.

Jingwen YangYing ZouXiaoyu LvJun ChenChen CuiJia SongMengmeng YangHuiqing HuJing GaoLongqing XiaLiming WangLi ChenXinguo Hou

Published in: Diabetology & metabolic syndrome (2024)

Didymin exhibits therapeutic potential in the treatment of HFD-induced IGT. This beneficial effect is attributed to the amelioration of PBC dysfunction through improved mitochondrial function.

Keyphrases

high fat diet induced
induced apoptosis
insulin resistance
oxidative stress
high fat diet
high glucose
cell cycle arrest
diabetic rats
endothelial cells
type diabetes
skeletal muscle
cell death
endoplasmic reticulum stress
signaling pathway
stress induced