The utility of whole-genome sequencing to inform epidemiologic investigations of SARS-CoV-2 clusters in acute-care hospitals.
Theodore S RaderVatsala Rangachar SrinivasaMarissa P GriffithKady WaggleLora Lee PlessAshley ChungSuzanne WagesterLee H HarrisonGraham M SnyderPublished in: Infection control and hospital epidemiology (2023)
Selectively utilizing reactive WGS helped identify cryptic SARS-CoV-2 transmission pathways and frequently changed the understanding and response to SARS-CoV-2 outbreaks. Until WGS is widely adopted, a selective reactive WGS approach may be highly impactful in response to healthcare-associated cluster investigations.