Astrocytic CD44 Deficiency Reduces the Severity of Kainate-Induced Epilepsy.
Patrycja K KrukKarolina NaderAnna Skupien-JaroszekTomasz WójtowiczAnna BuszkaGabriela Olech-KochańczykGrzegorz M WilczynskiRemigiusz WorchKatarzyna KalitaJakub WłodarczykJoanna DzwonekPublished in: Cells (2023)
Overall, our study indicates that CD44 signaling may be important for astrocytic coverage of synapses in the hippocampus and that alterations of astrocytes translate to functional changes in the pathology of epilepsy.