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Family history and pathogenic/likely pathogenic germline variants in prostate cancer patients.

Rachel A SabolElisa M LedetEllen JaegerWhitley HattonMarcus MosesAnjali LankfordAlexa ZaheriaPedro BarataJodi L LaytonBrian E LewisA Oliver Sartor
Published in: The Prostate (2021)
In men with a personal history of PCa, germline PV/LPVs were associated with a FDR with breast or ovarian cancer. Notably having FDRs with PCa does not predict for PV/LPVs. These data emphasize the contribution of FH in a data set with complete ascertainment of FH.
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