Subtype-Independent ANP32E Reduction During Breast Cancer Progression in Accordance with Chromatin Relaxation.

Garrett L RuffKristin E MurphyZachary R SmithPaula M VertinoPatrick J Murphy

Published in: BMC cancer (2021)

Our results indicate that ANP32E may function through chromatin state regulation to control breast cancer differentiation and tumor plasticity. This study sets a precedent for future computational studies of chromatin changes in carcinogenesis.

Keyphrases

dna damage
gene expression
transcription factor
genome wide
dna methylation
current status
single molecule
breast cancer risk
childhood cancer