Neuroprotection by Paeoniflorin against Nuclear Factor Kappa B-Induced Neuroinflammation on Spinal Cord Injury.
Bin WangWangying DaiLijun ShiHonglin TengXigong LiJing WangWujun GengPublished in: BioMed research international (2018)
These results suggest that the neuroprotective effects of PF are related to the inhibition of the NF-κB signaling pathway. And PF may be a therapeutic strategy in spinal cord injury.
Keyphrases
- nuclear factor
- spinal cord injury
- cerebral ischemia
- signaling pathway
- toll like receptor
- spinal cord
- neuropathic pain
- subarachnoid hemorrhage
- pi k akt
- high glucose
- brain injury
- diabetic rats
- lps induced
- blood brain barrier
- drug induced
- traumatic brain injury
- epithelial mesenchymal transition
- inflammatory response
- lipopolysaccharide induced
- cognitive impairment
- induced apoptosis
- cell proliferation