The Impact of Exercise on Redox Equilibrium in Cardiovascular Diseases.
Paweł SutkowyJoanna WróblewskaMarcin WróblewskiJarosław NuszkiewiczMartyna ModrzejewskaAlina WoźniakPublished in: Journal of clinical medicine (2022)
Cardiovascular diseases constitute the most important public health problem in the world. They are characterized by inflammation and oxidative stress in the heart and blood. Physical activity is recognized as one of the best ways to prevent these diseases, and it has already been applied in treatment. Physical exercise, both aerobic and anaerobic and single and multiple, is linked to the oxidant-antioxidant imbalance; however, this leads to positive adaptive changes in, among others, the increase in antioxidant capacity. The goal of the paper was to discuss the issue of redox equilibrium in the human organism in the course of cardiovascular diseases to systemize updated knowledge in the context of exercise impacts on the organism. Antioxidant supplementation is also an important issue since antioxidant supplements still have great potential regarding their use as drugs in these diseases.
Keyphrases
- oxidative stress
- cardiovascular disease
- physical activity
- public health
- high intensity
- anti inflammatory
- diabetic rats
- dna damage
- ischemia reperfusion injury
- molecular dynamics
- induced apoptosis
- endothelial cells
- molecular dynamics simulations
- cardiovascular risk factors
- healthcare
- wastewater treatment
- microbial community
- heart failure
- resistance training
- body mass index
- cardiovascular events
- type diabetes
- heat shock
- induced pluripotent stem cells
- atrial fibrillation
- body composition
- risk assessment
- electron transfer
- aqueous solution
- heavy metals
- signaling pathway
- metabolic syndrome
- smoking cessation
- drug induced