5-Fluorouracil disrupts ovarian preantral follicles in young C57BL6J mice.

Juliana Z AlmeidaLaritza F LimaLuís A VieiraCarolina MasideAnna C A FerreiraValdevane R AraújoAna B G DuarteRamon S RaposoSônia N BáoCláudio C CampelloLuiz F S OliveiraThayse P da CostaJosé Garcia AbreuJosé R FigueiredoReinaldo Barreto Oriá

Published in: Cancer chemotherapy and pharmacology (2021)

Altogether, our findings suggest that 5-FU can deleteriously affect the ovarian follicle reserve by reducing preantral follicles survival.

Keyphrases

high fat diet induced
middle aged
free survival
type diabetes
metabolic syndrome