Draft Genome Sequence of Mycobacterium tuberculosis Strain E186hv of Beijing B0/W Lineage with Reduced Virulence.
K V ShurK M KliminaN V ZakharevichDmitry A MaslovOlga B BekkerM V ZaychikovaE Y KamaevM A KravchenkoS N SkornyakovY ZhangV N DanilenkoPublished in: Genome announcements (2015)
We report a draft genome sequence of Mycobacterium tuberculosis strain E186hv, belonging to the Beijing B0/W lineage and isolated from a patient from Kurgan, Russia. This clinical isolate showed a reduced virulence phenotype unusual for this lineage and resistance to isoniazid, rifampin, ethambutol, pyrazinamide, and ofloxacin. We analyzed single nucleotide polymorphisms (SNPs) associated with virulence.
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