Improving the stability of 11C-labeled L-methionine with ascorbate.

Michael WoodsLeo LeungKari FrantzenJennifer G GarrickZhengxing ZhangChengcheng ZhangWade EnglishDon WilsonFrançois BénardKuo-Shyan Lin

Published in: EJNMMI radiopharmacy and chemistry (2017)

Our data suggest that to minimize degradation, ascorbate can be added to the 11C-MET formulation solution especially if it is not administered into patients soon after the end of synthesis.

Keyphrases

ejection fraction
newly diagnosed
prognostic factors
drug delivery
tyrosine kinase
computed tomography
patient reported outcomes
machine learning
pet imaging
data analysis
pet ct
solid state