Structural and functional connectivity alteration patterns of the cingulate gyrus in Type 2 diabetes.
Dongsheng ZhangYang HuangShasha LiuJie GaoWeirui LiuWanting LiuKai AiXiaoyan LeiXiaoling ZhangPublished in: Annals of clinical and translational neurology (2023)
The pACC and the RSC show dysfunctional connectivity before the appearance of structural abnormalities in T2DM patients. Abnormal FC of the pACC with the bilateral hippocampus and LPFC may imply a neural compensatory mechanism for memory function. These findings provide valuable information and new directions for possible interventions for the T2DM-related cognitive impairment.
Keyphrases
- cognitive impairment
- type diabetes
- functional connectivity
- resting state
- end stage renal disease
- glycemic control
- newly diagnosed
- ejection fraction
- chronic kidney disease
- white matter
- physical activity
- healthcare
- working memory
- patient reported outcomes
- adipose tissue
- brain injury
- weight loss
- blood brain barrier
- cerebral ischemia