Buprenorphine dosing for the treatment of opioid use disorder through pregnancy and postpartum.
Caitlin Eileen MartinCaroline ShadowenBhushan ThakkarTravis OakesTamas S GalF Gerard MoellerPublished in: Current treatment options in psychiatry (2020)
We present data from a retrospective chart review of patients at our institution describing trends in buprenorphine dosing during pregnancy and postpartum. Utilizing this information, we synthesize findings to provide clinical recommendations for providers. Changes in the total daily dose of buprenorphine used across pregnancy and through 12 months postpartum at the individual level do not follow consistent patterns, highlighting substantial individual variability. Altogether, buprenorphine dosing should be individualized through pregnancy and postpartum with frequent evaluations by providers and solicited input from patients.