Aster saponin A 2 inhibits osteoclastogenesis through mitogen-activated protein kinase-c-Fos-NFATc1 signaling pathway.

Xiang-Dong Su Seo Young Yang Saroj Kumar Shrestha Yunjo Soh

Published in: Journal of veterinary science (2022)

AS-A2 isolated from AT appears to be a viable therapeutic therapy for osteolytic illnesses, such as osteoporosis, Paget's disease, and osteogenesis imperfecta.

Keyphrases

signaling pathway
postmenopausal women
pi k akt
bone mineral density
epithelial mesenchymal transition
protein kinase
tyrosine kinase
induced apoptosis
bone loss
oxidative stress
endoplasmic reticulum stress