Diltiazem efficacy and CYP2D6 gene polymorphism in patients with atrial fibrillation with rapid ventricular response.
Mehmet UluturkAtakan YilmazMurat SeyitMert OzenAlten OskayAykut KemanciMedine UnalHande SenolAylin KoselerIbrahim TurkcuerPublished in: The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology (2023)
The presence of *2, *4 and *10 alleles was observed to significantly compromise the drug efficacy. *3 allele was found to bear no relation to the effect of diltiazem on achieving rate control.