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Which patients benefit from adding short-term psychodynamic psychotherapy to antidepressants in the treatment of depression? A systematic review and meta-analysis of individual participant data.

Ellen DriessenMarjolein FokkemaJack J M DekkerJaap PeenHenricus L VanGiuseppe MainaGianluca RossoSylvia RigardettoFrancesco CunibertiVeronica G VitriolAntonio AndreoliYvonne BurnandJaime López RodríguezValerio Villamil SalcedoJos W R TwiskFrederik J WienickePim Cuijpers
Published in: Psychological medicine (2022)
To our knowledge, this is the first study that examines moderators across trials assessing the addition of STPP to antidepressants. These findings need validation but suggest that depression severity and episode duration are factors to consider when adding STPP to antidepressants and might contribute to personalizing treatment selection for depression.
Keyphrases
  • depressive symptoms
  • major depressive disorder
  • sleep quality
  • healthcare
  • newly diagnosed
  • electronic health record
  • big data
  • physical activity
  • bipolar disorder
  • patient reported outcomes
  • deep learning
  • data analysis