Inflammasome activation mediated by oxidised low-density lipoprotein in patients with sleep apnoea and early subclinical atherosclerosis.

Carolina Cubillos-ZapataDavid Sanz-RubioSara García-TovarEnrique AlfaroPablo CuberoAna V GilJosé M MarinCarolina Cubillos-ZapataFrancisco García-Río

Published in: The European respiratory journal (2023)

OSA patients with eSA exhibit NLRP3 activation by IH and the presence of oxLDL capable of releasing TF, constituting a pathway for the interaction between dyslipidaemia and systemic inflammation in the development of atherosclerotic lesions.

Keyphrases

low density lipoprotein
positive airway pressure
obstructive sleep apnea
cardiovascular disease
sleep quality
sleep apnea