Retigabine, a potassium channel opener, restores thalamocortical neuron functionality in a murine model of autoimmune encephalomyelitis.
Luca FazioVenu Narayanan NaikRajeevan Narayanan TherpurakalFiorella M Gomez OsorioNicole RychlikJulia LadewigMichael StrüberManuela CerinaSven G MeuthThomas BuddePublished in: Brain, behavior, and immunity (2024)
Our results suggest that RTG treatment might robustly mitigate inflammation-induced altered excitability and preserve ascending information processing.